Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience
Therapeutic concept of memapsin 1 (BACE2) inhibition for treating type... | Download Scientific Diagram
RCSB PDB - 2EWY: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor
Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram
BACE2 variant identified from HSCR patient causes AD-like phenotypes in hPSC-derived brain organoids | Cell Death Discovery
BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance
Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram
The emerging role of β-secretases in cancer | Journal of Experimental & Clinical Cancer Research | Full Text
The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram
BACE2 Fusion Protein Ag9419 | Proteintech
BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library
JCI Insight - BACE2, a conditional β-secretase, contributes to Alzheimer's disease pathogenesis
Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies - Ghosh - 2019 - ChemMedChem - Wiley Online Library
BACE2 beyond β‐processing of APP, its neuroprotective role in cerebrovascular endothelium - Sáez‐Valero - Journal of Neurochemistry - Wiley Online Library
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
BACE2 Protein Overview: Sequence, Structure, Function and Protein Interaction | Sino Biological
Proteomic screen for BACE2 and BACE1 target identification. A,... | Download Scientific Diagram
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2 | Journal of Medicinal Chemistry
Anti-BACE2 antibody (ab5670) | Abcam
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions | ACS Chemical Neuroscience
BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein | PNAS
BACE2: A Promising Neuroprotective Candidate for Alzheimer's Disease - IOS Press
